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Asia Pacific Journal of Medical Toxicology
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Asia Pacific Journal of Medical Toxicology
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Ghorbani, H., Hedjazi, A., Zarif, D. (2014). Ethanol Concentration and Its Correlation with CNS Suppressor Drugs in Postmortem Subjects. Asia Pacific Journal of Medical Toxicology, 3(Supplement 1), 13-13. doi: 10.22038/apjmt.2014.2889
Hamideh Ghorbani; Arya Hedjazi; Daniel Zarif. "Ethanol Concentration and Its Correlation with CNS Suppressor Drugs in Postmortem Subjects". Asia Pacific Journal of Medical Toxicology, 3, Supplement 1, 2014, 13-13. doi: 10.22038/apjmt.2014.2889
Ghorbani, H., Hedjazi, A., Zarif, D. (2014). 'Ethanol Concentration and Its Correlation with CNS Suppressor Drugs in Postmortem Subjects', Asia Pacific Journal of Medical Toxicology, 3(Supplement 1), pp. 13-13. doi: 10.22038/apjmt.2014.2889
Ghorbani, H., Hedjazi, A., Zarif, D. Ethanol Concentration and Its Correlation with CNS Suppressor Drugs in Postmortem Subjects. Asia Pacific Journal of Medical Toxicology, 2014; 3(Supplement 1): 13-13. doi: 10.22038/apjmt.2014.2889

Ethanol Concentration and Its Correlation with CNS Suppressor Drugs in Postmortem Subjects

Article 24, Volume 3, Supplement 1, Spring 2014, Page 13-13  XML PDF (36 K)
Document Type: Original Article
DOI: 10.22038/apjmt.2014.2889
Authors
Hamideh Ghorbani1; Arya Hedjazi* 2; Daniel Zarif1
1Legal Medicine Research Center, Tehran, Iran
2Forensic Medicine Specialist, Legal Medicine Research Center, Tehran, Iran
Abstract
Background: Many studies have been done in order to interpret correctly the results of ethanol analysis and its related problems. Unfortunately, it was not easy to determine BAC rate, due to postmortem different conditions or personal and clinical differences in metabolism and excretion of ethanol. The time between death and autopsy, the environmental conditions (temperature and humidity) are important factors to be taken into account. Concentration of ethanol in vitreous humor depends on the person’s age, drinking experience and degree of tolerance development.
Methods: In this study, concentration of ethanol in vitreous humor was assessed in 100 cases with consumption of CNS suppressor drugs that were detected in urine and tissue.
Results: The toxicity of ethanol is often considerably enhanced by the concomitant use of other drugs with their site of action in the brain especially opiates, antidepressants and some sedative hypnotics.
Conclusion:  Death occurs in low concentration of alcohol consumed simultaneously with CNS suppressor drugs.
Keywords
Autopsy; Central Nervous System Agents; Ethanol; Vitreous Body
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