Document Type : Original Article
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Iran.
Department of Internal Medicine Faculty of Medicine Tabriz University of Medical Sciences Tabriz,Iran
Department of Medical Surgical Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Iran.
Department of Internal Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Allergy and Clinical Immunology, Pediatric Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Tabriz university of medical sciences
Background: Alcohol poisoning causes several clinical signs and symptoms. The present study was carry out to examine the epidemiology and characteristics of poisoned patients with alcohol, who were treated at the Sina hospital Tabriz in Iran.
Purpose: The purpose of this study was to determine the clinical features and laboratory tests in alcohol poisoning.
Methods: In the current expressive cross-sectional report, during 2018-2020 details were obtained over referring to all 91 alcohol poisoned patients’ files. The data were obtained based on the time interval between poisoning and time of admission to hospital. The data were then analyzed through SPSS software and descriptive statistics.
Results: All over this period, 91 cases of alcohol-poisoned patients were hospitalized, out of which 81 patients (90%) were male and 9 patients (10%) were female. Mostly ethanol was used in poisoning (68.7%) and methanol (28%). 56% of alcohol poisoned patients used alcohol for euphoria, 33.3% used it for suicide, and 10.7% used it recreationally. Most poisoning symptoms occurred between 6 to 12 hours after poisoning. Neurological symptoms occurred among 70 patients (76.9%), 52 cases (57%) had gastrointestinal symptoms, and 19 patients (20.8%) had visual symptoms.
Conclusion: Most of poisoned patients were men below the age of 30 years and unemployed. Alcohol consumption for euphoria were more common among people with higher education occasionally for recreation and those with high school education level were for suicide to get rid of problems from living environment. Particular attention of health authorities should be directed towards alcohol drinking prevention measures as well as production and availability of surrogate alcohols in the community.
- Gutjahr E, Gmel G, Rehm J. Relation between Average Alcohol Consumption and Disease: An Overview. Eur Addict
Res. 2001; 7:117–27.
2. Kanny D, Brewer RD, Mesnick JB, Paulozzi LJ, Naimi TS, Lu H. Vital signs: alcohol poisoning deaths-United States, 2010-2012. MMWR Morb Mortal Wkly Rep. 2015; 63(53):1238-42.
3. Centers for Disease Control and Prevention. Vital signs: binge drinking prevalence, frequency, and intensity among adultsUnited States, 2010. MMWR Morb Mortal Wkly Rep.2012; 61(1):14-19.
4. Rehm J, Zatonksi W, Taylor B, Anderson P. Epidemiology and alcohol policy in Europe. Addiction. 2011; 106(1): 11-19.
5. Chen F, Wen JP, Wang XP, Lin QM, Lin CJ. Epidemiologyand characteristics of acute poisoning treated at an emergency center. World J Emerg Med. 2010; 1(2): 154–56.
6. Liu Q, Zhou L, Zheng N, Zhuo L, Liu Y, Liu L. Poisoning deaths in China: Type and prevalence detected at the Tongji
Forensic Medical Center in Hubei. Forensic Sci. Int. 2009; 193(1–3): 88–94.
7. Delirrad M, Mohammadi AB. New methanol poisoning outbreaks in Iran following COVID-19 pandemic. Alcohol
Alcohol. 2020; 55(4):347-48.
8. Shokoohi M, Rahimi-Movaghar A, Noroozi A, Karamouzian M. A public health approach to alcohol use and its related harms in Iran. Lancet Public Health. 2019; 4:175-76.
9. Mohammad khani SH. Prevalence of Cigarette Smoking, Alcohol Drinking and Illegal Drugs Use among Iranian
Adolescents. J Kerman Univ Medical Sci. 2011; 19(1): 32-48.
10. Mostafazadeh B, Egbali H. An epidemiologic study on methyl alcohol poisoning in Tehran, Iran. Asia Pac. J. Med. Toxicol. 2014; 14(3): 8.
11. Mortezabagi HR, Tagizadieh M, Moharamzadeh P, Pouraghaei M, Kahvareh Barhagi A, Shahsavari Nia K.
Epidemiologic of alcohol poisoning and its outcome in the north- west of Iran. Emergency. 2015; 3(1): 27-32.
12. Cherpitel CJ, Borges GL, Wilcox HC. Acute Alcohol Use and Suicidal Behavior: A Review of the Literature. Alcoholism: Alcohol Clin Exp Res. 2004; 28(5): 18S–28S.
13. Room R, Babor T, Rehm J. Alcohol and public health. The Lancet. 2005; 365(9458): 519-530.
14. Rehm J, Baliunas D, Borges GLG, Graham K, Irving H, Kehoe T et al. The relation between different dimensions of
alcohol consumption and burden of disease: an overview. Addiction. 2010;105: 817- 843.
15. Zaridze D, Boreham J, Boroda, Rostislav Karpov R, Alexander Lazarev A, et al. Alcohol and cause-specific mortality in Russia: a retrospective case–control study of 48557 adult deaths. The Lancet. 2009; 373(9682): 2201–2214.
16. Poikalainen K, Leppanen K, Vuori E. Alcohol sales and fatal alcohol poisonings: a time series analysis. Addiction. 2002; 97(8): 1037-40.
17. Farkas A, Kemény L. Psoriasis and alcohol: is cutaneous ethanol one of the missing links? Br J Dermatol. 2010; 162 (4): 711-716.
18. Jafarpur M, Ebrahimzadeh AR. Study of ovarian Histological changes after Ethanol consumption. Intern Med Today. 2006; 11(4): 19-23.
19. Moon CS. Estimations of the lethal and exposure doses for representative methanol symptoms in humans. Ann Occup Environ Med. 2017; 29(1): 44.
20. Mertens JR, Lu YW, Parthasarathy S, Moore C, Weisner CM. Medical and Psychiatric Conditions of Alcohol and Drug Treatment Patients in an HMO: Comparison With Matched Controls. Arch Intern Med. 2003; 163(20): 2511-17.
- 21. Kraut JA, Kurtz I . Toxic alcohol ingestions: clinical Features, diagnosis, and management, Clin J Am Soc Nephrol. 2008; 3(1): 208-222.
22. Vonghia L, Leggio L, Ferrulli A, Bertini M, Gasbarrini G, Addoloratoet G. Acute Alcohol Intoxication. Eur J Intern Med. 2008; 19(8): 561-67.
23. Jammalamadaka D, Raissi S. Ethylene glycol, methanol and isopropyl alcohol intoxication. Am J Med Sci. 2010; 339(3): 276-281.
24. Moghadamnia AA, Abdollahi M. An epidemiological study of poisoning in northern Islamic Republic of Iran. East Mediterr Health. 2002; 8(1): 88-94.
25. Hashemi N, Zadeh-Bagheri G, Ghafarianshirazi HR. Opiate and Alcohol abuse and related factors in Yasouj University of Medical Sciences (south of Iran). Life Science Journal. 2012; 9(3): 1195-98.
26. Centers for Disease Control and Prevention. USA. Alcohol use and binge drinking among women of childbearing age--United States, 2006-2010. MMWR Morb Mortal Wkly Rep. 2012; 61(28):534-38.
27. McMahon DM., Winstead SH, weant KA. Toxic alcohol ingestions: Focus on Ethylene Glycol and Methanol. Adv Emerg Nurs J. 2009; 31(3): 206-213.
28. Sanap M, Chapman MJ. Severe ethanol poisoning: a case report and brief review. Crit Care Resusc. 2003; 5(2):106-8.
29. Tuusov J, Vals K, Tõnisson M, Riikoja A, Denissov G, Väli M. Fatal poisoning in Estonia 2000–2009. Trends in illegal drugrelated deaths. Journal of J Forensic Leg Med. 2013; 20(1): 51-56.
30. Jones AW, Kugelberg FC, Holmgren A, Ahlner J. Drug poisoning deaths in Sweden show a predominance of ethanol in mono-intoxications, adverse drug–alcohol interactions andpoly-drug use. Forensic Sci Int. 2011; 206(1–3): 43–51.
31. Yoon YH, Stinson FS, Yi H, Dufour CM. Accidental* Alcohol Poisoning Mortality in the United States, 1996–1998. Alcohol Res Health. 2003; 27(1): 110–118.
32. McDowell R, Fowles J, Phillips D. Deaths from poisoning in New Zealand: 2001–2002. N Z Med J. 2005; 118 (1225): 1-9.
33. Brvar M, Bunc M. High-degree atrioventricular block in acute ethanol poisoning: a case report. Cases J. 2009; 2(8559): 1-3.
34. Hovda KE, Hunderi OH, Tafjord AB, Dunlop O, Rudberg N, Jacobsen D. Methanol outbreak in Norway 2002–2004: epidemiology, clinical features and prognostic signs. J. Intern. Med. 2005; 258( 2): 181-190.
35. Galvez-Ruiz A, Elkhamary SM, Asghar N, Bosley TM. Visual and neurologic sequelae of methanol poisoning in Saudi Arabia. Saudi Med J. 2015; 36(5):568–574.
36. Jammalamadaka D. Raissi S. Ethylene Glycol, Methanol and Isopropyl Alcohol Intoxication. Am J Med Sci. 2010; 339(3):276-281