Normal Acid Base Balance in aluminum phosphide poisoning: Case reports of a rare presentation

Saffaei, Ali; Zahed, Narges Sadat; Shadnia, Shahin; Erfantalab, Peyman; Rahimi, Mitra

doi:10.22038/apjmt.2023.21890

Normal Acid Base Balance in aluminum phosphide poisoning: Case reports of a rare presentation

Document Type : Case Report

Authors

Ali Saffaei ¹

Narges Sadat Zahed ²

Shahin Shadnia ³

Peyman Erfantalab ⁴

Mitra Rahimi ⁵

¹ Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

² Department of Nephrology, Shahid Beheshti University, Loghman-Hakim Hospital, Tehran, Iran.

³ Toxicology Research Center, Excellence Center of Clinical Toxicology AND Department of Clinical Toxicology, Loghman Hakim Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

⁴ Toxicological Research Center, Department of Clinical Toxicology, Shahid Beheshti University of Medical Sciences, Loghman Hakim Hospital, Tehran, Iran.

⁵ Shahid Beheshti University of Medical Sciences

https://doi.org/10.22038/apjmt.2023.21890

Abstract

Introduction: Aluminum phosphide (AlP) is an effective fumigant and rodenticide which is a commonly used agent for suicide in parts of developing countries. AlP poisoning results in serious manifestations involving many vital organs and it has high mortality. Electrolyte and metabolic abnormalities including metabolic acidosis is a common problem in AlP poisoning.
Case report: Here, we report two cases of AlP poisoning who take AlP tablets intentionally. The therapeutic intervention initiated for both of them including glucose, insulin, and potassium (GIK) protocol, antioxidants agents, intravenous magnesium, intravenous calcium, and norepinephrine. The arterial blood samples obtained in a serial manner and interestingly it showed no abnormality.
Conclusion: This is first cases of AlP poisoning with normal acid base balance which emphasis the importance the early initiation of therapeutic intervention

Keywords

Aluminum phosphide

acidosis

Poisoning

Toxicity

blood gas

20.1001.1.23222611.2023.11.4.8.9

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