1 Occupational and Environmental Health, School of Population and Public Health, The University of British Columbia

2 1. Division of Occupational and Environmental Health, School of population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada.


The Covid-19 pandemic has led to a ‘new normal’, where the general public is adopting infectious disease prevention measures set by scientists and health officials. Current COVID-19 prevention measures to reduce or stop transmission include handwashing, physical distancing, stay home orders, and quarantine, as well as encouraging the use of masks in public areas by community members.


Tackling the COVID-19 pandemic requires all health sectors, even those not traditionally involved with infectious diseases. Therefore, a holistic approach is required to mitigate its spread. Toxicologists play an imperative role in developing and implementing such measures in a viral epidemic (1). Their robust and pragmatic training in risk assessment and management, such as on handling the hazardous materials, can be mobilized to support the Covid-19 response.


Medical toxicologists, in particular, have a key role to play in acting as a knowledge resource for physicians and “voice of caution” for the public (2).This includes advising clinicians on potential adverse reactions to COVID-19 therapeutic options, including serum sickness and ventricular dysrhythmias from indicated to controversial use of recombinant protein therapeutics chloroquine as well as investigating the impact of the virus on drug metabolism (which will greatly impact medication success, viral infectivity and patient outcomes). Moreover, toxicologists can help optimize existing medical and public health systems, by helping identify at risk populations (ex- individuals suffering from substance abuse) and establishing standards for effective mask usage for community members(3). Medical toxicologists are well experienced in conducting observational studies and randomized controlled trials. They have scientific knowledge, personnel and logistics that can be mobilized to conduct research on the infectious pandemic.



Face masks, intended to trap droplets released when someone talks, coughs or sneezes, mitigate the spread of COVID-19 by controlling its source. This means that any mask, including  those worn by asymptomatic individuals is potentially infected at the time of disposal(4).


Current recommendations on discarding used masks emphasize the importance of not touching the front of the mask during removal and washing hands using soap and water for at least 20 seconds or using alcohol-based hand sanitizer after discarding and disposing of masks in a covered container. However, as mask disposal information must be sought on public health websites and can be difficult to find, indecorous disposal of masks is on the rise and may allow the virus to flourish. When worn or discarded incorrectly, masks themselves become a source of infection (5). This is particularly important for long-term care facilities or households with elderly and immunocompromised individuals, where improperly discarded masks can lead to severe repercussions.


Medical toxicologists, with immense experience with risk assessment analysis of hazardous materials, are well positioned to incorporate proper mask disposal practices into public COVID-19 communication. A key message should encourage the public to carry disposal bags to temporarily store masks in areas where a garbage bin may not be easily accessed. Secondly, garbage bins where the masks are discarded should be labelled, to discourage mask disposal in improper locations (ex. recycling bins).



Wherever possible, barriers to proper disposal methods should be reduced to improve public compliance. However, we must also consider  the impact of such guidelines on marginalized groups and ensure that stricter disposal guidelines do not augment existing  socioeconomic and health inequities (6).

It is important to remember that Individual and community capacity to comply with disposal guidelines may vary depending on public knowledge, socioeconomic determinants and health system infrastructure. At the same time, we must craft disposal guidelines keeping environmental injustice in mind and the harsh reality that individuals living in poverty are more likely to be exposed to toxins(7). Mask disposal guidelines must balance the need for stringent COVID-19 prevention measures in high risk areas as well as the availability of resources.




Hazmat specialists and medical toxicologists should be consulted in the development of mask disposal guidelines that are specific to the challenges faced in a particular region or community. Additionally, toxicologists can play a vital role in developing educational and awareness materials for both the general public and physicians about disposal guidelines.

Moving forward, we must modify current toxicology curricula to include strategies for communicable disease management to ensure that emerging toxicologists are equipped to adequately address the dynamic needs of a pandemic (8). On a larger scale, we should highlight the importance of toxicologists in public health education to raise awareness and interest in toxicologic science (9,10).


The COVID-19 pandemic has reinforced the strategy that all branches of health/medicine including toxicologists are needed to be on board to manage the pandemic. In the fight against the COVID-19 pandemic, we must mobilize all resources to research, develop and implement guidelines pertaining to hazardous waste disposal. We have summarized the guidelines for the safe disposal of masks and used tissue papers from different public health sources partly derived from toxicology related references (Table 1).


We acknowledge the contribution of Deyvika Srinivasa (Faculty of Science, University of British Columbia) in developing the manuscript of this article.

11.    Canada P. COVID-19 non-medical masks and face coverings: How to put on, remove and clean - Canada.ca [Internet]. Canada.ca. 2020 [cited 26 August 2020]. Available from: https://www.canada.ca/en/public-health/services/diseases/2019-novel-coronavirus-infection/prevention-risks/how-put-remove-clean-non-medical-masks-face-coverings.html
19.    [Internet]. Fernie.civicweb.net. 2020 [cited 26 August 2020]. Available from: https://fernie.civicweb.net/document/108369
20.    [Internet]. Princeedwardisland.ca. 2020 [cited 26 August 2020]. Available from: https://www.princeedwardisland.ca/sites/default/files/publications/1031_mask4.pdf